Effect of EDTA Chelation Therapy Plus
Multi-vitamin/Trace Mineral Supplementation Upon Vascular Dynamics
E.W. McDonagh, DO, C.J. Rudolph, DO, and E. Cheraskin, MD, DMD
Dr.
E.W. McDonagh is founder of the McDonagh Medical Center in
Gladstone, Missouri, where he practices with Dr. C..J.
Rudolph. Dr. E. Cheraskin is Professor Emeritus and former
Chairman of the Department of Oral Medicine at the
University of Alabama.
ABSTRACT:
A study of 117 lower extremities in 77 elderly patients with documented
occlusive peripheral vascular stenosis, diagnosed by the Doppler systolic
ankle/brachial (ankle/arm) blood pressure ratio is reported. This study
showed that intravenous ethylene diamine tetraacetic acid (EDTA) chelation
therapy with supportive multivitamin/trace mineral supplementation improved
arterial blood flow to the legs significantly after approximately 60 days
and 26 infusions (P<0.001).
[Note:
Blood pressure is normally higher in the ankles than in the arms. An A/B
ratio of less than approximately 1.0 is considered abnormal and is an
indication of blockage to the flow of blood to the legs]
Effect of EDTA
Chelation Therapy with Vitamin/Mineral Supplementation
upon Ankle-Brachial Systolic Pressure
All Patients
Sample Size
Ankle/Brachial
Pressure
Mean Percentage Change
Significance of the
Difference of the Means
1 initial
2 final
117
117
0.77±0.22
0.94±0.17
+ 22%
t=8.0041 P<0.001*
Lower (poorer) patients, initial A/B
ratio less than 0.80
3 initial
4 final
46
46
0.55±0.19
0.71±0.25
+ 29%
t=3.9771 P<0.001*
Higher (better) patients, initial A/B
ratio greater than 0.80
5 initial
6 final
71
71
0.91±0.06
1.08±0.17
+ 19%
t=8.9790 P<0.001*
*statistically significant difference of the means
Journal of Advancement in Medicine Volume 2, Numbers 1/2, Spring/Summer
1989
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